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Investor Presentaiton

Company overview Financial performance Oncology Financial review 2022 priorities Appendix Innovation: Pipeline overview Innovation: Clinical trials Immunology Ophthalmology Neuroscience Respiratory Disease remibrutinib - BTK inhibitor NCT04109313 (CLOU064A2201E1) Chronic spontaneous urticaria (CSU) Indication Phase Phase 2 Patients 250 Primary Long-term safety and tolerability Selected dose of LOU064 taken orally twice a day (morning and evening) from day 1 to week 52 Patients with CSU who have participated in preceding studies with LOU064 Outcome Measures Arms Intervention Target Patients Read-out Milestone(s) H2 2022 Publication Primary 2023 References Abbreviations Cardio-Renal Global Health Biosimilars 73 Investor Relations | Q2 2022 Results NOVARTIS | Reimagining Medicine
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