Investor Presentaiton
Epidemiology, Determinants and Dynamics of
Cholera in Pakistan: Gaps and Prospects for
Future...
Article in Journal of the College of Physicians and Surgeons--Pakistan: JCPSP · November 2014
Source: PubMed
Table 1: Epidemiology and determinants of cholera infection in Pakistan from published research articles from 1995 - 2010.
Year of
publication
No. of articles
published
Agent
Host
Environment
1995-2000 2
2001-2005 8
2006-2010 7
1989-1992: Major serotype responsible was
Ogawa 01
1993-94: Reappearance of non-01 (0139)
1990-98: Ogawa biotype El Tor predominant
1999: Emergence of classical Ogawa 01 serotype
2000-2001: Predominant serotype non-01 (0139).
However, classical Ogawa also exist in this period.
2002-2004: El Tor biotype of Ogawa responsible for
outbreaks and epidemics of cholera in this period.
2004-2005: upsurge in the isolation of Vibrio
cholerae Inaba.
2008: predominant serotype 01 biotype El Tor.
All ages and both gender are at risk of
getting disease.
Environmental factors of cholera
infection were not explored in
Non-01 involved mostly adults, youngest child this period in Pakistan.
infected with cholera was 7 days old.
Mean age for child affected with El Tor was
31+/-34 months.
Mean age for non 01 infection was 40 years
while for 01 it was 23 years.
Both gender at risk.
Poverty and low education were also
important host factor determinants. Severity
of infection and fever along with symptoms
of diarrhea common with non 01.
Involvement of both children and adults with
younger age affected with Ogawa 01 and
older age in non-01 infection.
No primary research done in
Pakistan to explore environmental
aspect of cholera infection.
Environmental factors such as
water contamination with
V. cholerae, use of toilet other
than flush system associated
with increased infection.
Journal of the College of Physicians and Surgeons Pakistan 2014, Vol. 24 (11): 855-860
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