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Investor Presentaiton

Radiopharmaceutical sector transactions The radiopharmaceutical market is niche and highly acquisitive Advanced Accelerator Applications ENDOCYTE ALGETA Completed Phase 3 with LutatheraⓇ in Sep 2015, market entry was early 2018 Acquired by Novartis for USD3.9 billion in cash in 2018 Licensed PSMA-617 after Phase 2a for ~USD14 million upfront with additional milestones and royalties. Their market cap. over USD1 billion after FDA meeting and financing to start a Phase 3 trial October 2018, Novartis announced the acquisition of Endocyte for USD2.1 billion Bayer acquired Algeta ASA for USD2.9 billion in 2014 to develop its metastatic prostate-cancer product Xofigo® Curium™ LIFE FORWARD BLUE EARTH DIAGNOSTICS A Bracco Company Progenics Pharmaceuticals IBA Molecular acquired Mallinckrodt's nuclear imaging business for USD690 million in 2017 Syncona completed sale of Blue Earth Diagnostics to Bracco Imaging for $476.3m (£390.2m) in 2019 Acquired by Lantheus Holdings for approximately USD430 million in 2020 CLARITY 2014 ME 4
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