Investor Presentaiton

Investor presentation Full year 2018 The total branded diabetes market has a global value of DKK ~270 billion annually Slide 47 2016/17 2017/18 Growth Global diabetes market The USA -7% -1% bDKK bDKK 269 266 150 148 139 250 100 -16% 77 65 50 18% 29 34 -11% 3% 28 25 14 15 200 -9% 144 150 132 0 Total Insulin GLP-1 DPP-IV SGLT-2 Rest of world bDKK 100 -3% 18% 150 64 62 6% 121 127 -1% 50 45 24% 100 2% 50 38 67 66 18% 27 22 50 36 37 9 11 62% 8 13 Total Insulin GLP-1 DPP-IV SGLT-2 Total Insulin GLP-1 DPP-IV SGLT-2 2016/17: Covers the four quarters from Q3 2016 to Q2 2017, except for Boehringer Ingelheim share of Trajenta which covers full year 2016 2017/18: Covers the four quarters from Q3 2017 to Q2 2018, except for Boehringer Ingelheim share of Trajenta which covers full year 2017 Note: Constant exchange rates between periods and Boehringer Ingelheim's regional split is based on regional split from 2017 Annual report for prescription medicine Source: Company reported sales novo nordisk

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