Investor Presentaiton

Investor presentation Full year 2018 Slide 51 Stable global insulin volume growth 18% 16% 14% 12% 10% 8% 6% 4% 2% Regional insulin volume growth North America Region China Region Europe Region J&K Regional insulin volume market split Region Europe Region J&K Region AAMEO North America Region LATAM Region China World 100% 80% 60% 40% 3% 20% Region AAMEO Region LATAM 3% 3% 10% 22% Nov 2013 Note: Data is sensitive to changes in IQVIA data collection and reporting methodology. Source: IQVIA monthly MAT Nov, 2018 volume figures 0% 0% Nov 2013 Nov 2018 Reg: Region; J&K: Japan & Korea; AAMEO: Africa, Asia, the Middle-East and Oceania; LATAM: Latin America Note: Data is sensitive to changes in IQVIA data collection and reporting methodology Source: IQVIA monthly MAT Nov, 2018 volume figures changing diabetes 32% 30% Nov 2018 novo nordisk

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