Half-Year 2022 Financial and Clinical Trials Update

Geographical sales split by Divisions and Group* CHFM HY 2021 HY 2022 % change CER Pharmaceuticals Division 21,671 22,347 +3 United States 10,802 11,363 +1 Europe 4,485 4,104 -4 Japan 1,808 2,202 +34 International 4,576 4,678 +2 Diagnostics Division 9,042 9,948 +11 United States 1,849 2,511 +31 Europe 3,574 2,799 -17 Japan 324 380 +29 International 3,295 4,258 +30 Group 30,713 32,295 +5 United States 12,651 13,874 +5 Europe 8,059 6,903 -10 Japan 2,132 2,582 +33 International 7,871 8,936 +14 CER-Constant Exchange Rates; * Geographical sales split shown here does not represent operational organization Roche 164

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