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35 Jefferson Patient HPI: A 32-year-old woman with RDEB and history of several cutaneous SCCs with nodal involvement who failed multiple treatment modalities presented to Jefferson in 2022. Medical history: Esophageal Strictures Malnutrition Loss of teeth Anemia Prior treatments: Excision: left hand, scalp SCC (2015) Mohs: right and left arm SCC (2015), left wrist SCC (2017) Cetuximab (2016) Pembrolizumab (11/2018-1/2019, 4 cycles) Excisions: right hip, thigh, arm, ankle, foot, left hand, wrist, thigh, knee (2020-2022) Medications: • Iron infusions, PRN Gabapentin, PRN Ibuprofen, PRN Acetaminophen with codeine, PRN Hydroxyzine, PRN Banner, et al. poster 613, ISID 2023 0 ONCONOVA THERAPEUTICS

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