Investor Presentaiton

Gel Implants COMPELLING 10-YEAR CLINICAL VALIDATION¹ The largest breast implant study of its kind Complication Primary Augmentation Complication Rates 1,2 Mentor 10-Yr (N=552) Allergan 10-Yr (N=455) Sientra 10-Tr (N=1,116) Number of Implants 2,230 1,102 908 MRI Cohort Patients 398 220 158 Rupture (MRI cohort) 8.7% 24.2% 9.3% Reoperation 24.2% 25.5% 36.1% Capsular Contracture III/IV 12.9% 12.1% 18.9% Low Low Rupture Rate 2,3 Low Capsular Contracture Rate 2,3 Reoperation Rate 2,3 FOR INFORMATIONAL PURPOSES ONLY - differences exist between trial designs and subject populations. No head-to-head study has been conducted comparing Sientra's breast products to these products. 1 Stevens WG, Calobrace MB, Alizadeh A, Zeidler KR, Harrington JL, d'Incelli RC. Ten-year core study data for Sientra's Food and Drug Administration - approved round and shaped breast implants with cohesive silicone gel. Plast Reconstr Surg. 2018;141(4S):7S-19S; 2 Calobrace MB, Schwartz MR, Zeidler KR, Pittman TA, Cohen R, Stevens WG. Long-term safety of textured and sientra, smooth breast implants. Aesth Surg. 2017;1-11.(4S): 7S-19S: 3 primary augmentation cohort 8

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