Phesgo and Tecentriq Performance and Approvals slide image

Phesgo and Tecentriq Performance and Approvals

Q1 2023: Strong underlying sales excluding COVID-19 decline Group sales -3% driven by expected decline in COVID-19 testing · Strong Pharma performance (+9%) driven by ongoing portfolio rejuvenation . Good Diagnostics base business growth (+4%) • COVID-19 sales decline in line with FY 2023 expectations Roche Growth supported by key products and strong launches • • • Pharma key products Vabysmo, Ocrevus, Hemlibra, Evrysdi, Tecentriq, Perjeta, Phesgo and Polivy continuing to grow strongly Key Pharma approvals: Polivy in 1L DLBCL in the US, Hemlibra in moderate hem A in the EU, Columvi (glofitamab) in 3L+ DLBCL in Canada Diagnostics: launches of new tests in oncology, navify Algorithm Suite and navify Marketplace Update on pipeline newsflow in 2023 • • Positive Phase III results for Tecentriq + Avastin in adjuvant HCC and crovalimab in PNH achieved Pharma: 14 upcoming late-stage read-outs incl. 2 NMEs (tiragolumab, SRP-9001) and important line extensions for Ocrevus, Tecentriq, Venclexta, TNKase, Alecensa and Lunsumio • Diagnostics: CCM Vertical, LightCycler Pro, Anti-HEV IgG/IgM, HBeAg Quant, and IL-6 Neonatal sepsis Growth rates at CER (Constant exchange Rates); DLBCL= diffuse large B-Cell lymphoma; NME=new molecular entity; HCC-hepatocellular carcinoma; PNH=paroxysmal nocturnal hemoglobinuria 6
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