Q1 2023 Results slide image

Q1 2023 Results

Company overview Financial review Conclusions Innovation: Pipeline overview Financial performance Cardiovascular Immunology JakaviⓇ - JAK1/2 inhibitor Indication Phase NCT03491215 REACH4 (CINC424F12201) Acute graft versus host disease Phase 2 Patients 45 Primary Measurement of PK parameters Outcome Measures Overall Response Rate (ORR) Arms Ruxolitinib Appendix Innovation: Clinical trials Neuroscience Oncology Intervention Target Pediatric patients with grade II-IV acute graft vs. host disease after allogeneic hematopoietic stem cell transplantation Patients Readout 2023 Milestone(s) Publication TBD 72 Investor Relations | Q1 2023 Results JakaviⓇ- JAK1/2 inhibitor References Abbreviations Other Indication NCT03774082 REACH5 (CINC424G12201) Chronic graft versus host disease Phase Phase 2 Patients 45 Primary Outcome Overall Response Rate (ORR) Measures Arms Intervention Target Patients Ruxolitinib 5mg tablets / pediatric formulation Pediatric subjects with moderate and severe chronic Graft vs. Host disease after allogeneic stem cell transplantation Readout Milestone(s) Publication 2023 TBD NOVARTIS | Reimagining Medicine
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