American Thoracic Society - Sanofi Investor Call
Tackling Type 2 inflammatory disease.
Type 2 inflammatory pathway
Targets
Allergens and parasites
Key immune cells
Key cytokines
Th2
ILC2 Mast cell B-cell Basophil Eosinophil
IL-4
IL-5
IL-13
Dysregulated type 2 immunity leads to chronic
systemic diseases manifesting in different organ systems
Gandhi NA, et al. Targeting key proximal drivers of type 2 inflammation in disease. Nat Rev Drug Discov. 2016; 15(1): 35-50. McCormick J, et al. Insights
into the Implications of Coexisting Type 2 Inflammatory Diseases. J Inflamm Res. 2021; 4: 4259-4266
10 ATS Investor Call
sanofi
Leadership strategy
> Lead with science
Focus on highest unmet
need with first-in-class
and best-in-class
opportunities
Anchor on strategic pillars
> Be bold and execute
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