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PRICE/RATE/VOLUME EFFECT ON REVENUE Lilly Millions Q2 2023 Amount Price FX Rate Volume Total CER U.S. $5,531 2% 39% 41% 41% EUROPE 1,178 (6)% 1% 12% 7% 6% JAPAN 456 1% (7)% 7% 7% CHINA 399 (1)% (7)% 20% 13% 20% REST OF WORLD 748 (1)% (3)% 20% 16% 19% TOTAL REVENUE $8,312 (0)% (1)% 29% 28% 29% 1H 2023 Amount Price FX Rate Volume Total CER U.S. $9,968 (2)% 11% 9% 9% EUROPE 2,269 (6)% (3)% 13% 5% 7% JAPAN 843 - (10)% 7% (3)% 7% CHINA 772 (11)% (7)% 20% 2% 9% REST OF WORLD 1,422 1% (2)% 4% 2% 4% TOTAL REVENUE $15,272 (3)% (2)% 11% 7% 8% Numbers may not add due to rounding = CER price change + volume change Not for promotional use 2023 Q2 EARNINGS 8

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