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Novartis Investor Presentation

New Novartis: Our strategy Our focus Our priorities Improved financials Launch excellence > High-value innovation Operational excellence Strengthen foundations Conclusion Abbreviations 3. High-value innovation Key near-term readouts (2023 - 2024) for high value assets... Kisqali NATALEE trial in adjuvant breast cancer testing both high-risk and intermediate-risk patients with final Phase 3 readout expected in 2023 Iptacopan APPLY-PNH trial with expected Phase 3 readout in H2 2022, followed by other indications in 2023 Pluvicto PSMAfore trial in mCRPC (post-ARDT, pre-taxane) with expected readout end of 2022 / early 2023 PSMAddition trial in mHSPC with expected readout in 2024 21 21 Remibrutinib CSU Phase 3 REMIX-1 and -2 trials with expected readout in 2024 and Multiple sclerosis Phase 3 REMODEL-1 and -2 trials with expected readout in 2025 Scemblix 1L CML-CP trial with expected readout in 2024 Unprobabilized peak sales of indications in late-stage development: > USD 1bn > USD 2bn > USD 3bn Novartis Investor Presentation | September 22, 2022 1 | NOVARTIS | Reimagining Medicine
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