Investor Presentaiton

Strong vaccine response observed with SP0125 First administration 100 80 60 60 vaccine response rate (%) in subjects never exposed to RSV* 40 40 20 20 0 RSVt LD RSVt Placebo HD Two dose regimen * Absence of prior exposure to RSV was determined by measuring serum IgA before vaccination 34 Vaccines Investor Event RSVt LD RSVt HD Placebo sanofi > Strong (93%) vaccine response after two administrations of the High dose formulation > Marginal difference between the Low and High dose formulations

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