BioNTech Investor Day Presentation Deck

2 Variant-adapted vaccines I GMTs in participants without evidence of infection up to 1 month after study vaccination: Immunogenicity subset NT50 (titer) GMT 10,000 1,000 100 Internal data. 10 GMFR BNT162b2 (30 g) 74.3 455.8 I Prevax 1 MPD 5.8 BNT162b2 (60 g) 103.3 727.3 Prevax 1 MPD 6.9 BNT162b2 OMI BNT162b2 OMI (30 g) (60 g) 73.9 1014.5 I Prevax 1 MPD 13.5 70.5 1435.2 I Prevax 1 MPD 19.6 Bivalent (30 g) 77.2 711 Prevax 1 MPD 9.1 Bivalent (60 g) 81.6 900.1 Prevax 1 MPD 10.9 NUA CAR Pandemic prep. Pfizer BIONTECH Pfizer 70

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