Investor Presentation Q1 2023 slide image

Investor Presentation Q1 2023

54 Investor presentation First three months of 2023 Novo NordiskⓇ Large opportunity for activating more people with obesity to seek treatment and increasing the number of prescribers ONCE-WEEKLY wegovy® semaglutide injection 2.4 mg WegovyⓇ patient characteristics in the US 70% 31% 81% 37.8 of patients new to anti- obesity medication¹ of patients are female Average BMI of patients have ≥3 co- morbidities Of the people with overweight or obesity in the US, almost 90% have a weight-related comorbidity BMI (million of people) 27-30 (43) 30-35 (52) 140 No obesity-related comorbidity1 7 (41%) 6 (35%) 35-40 (25) 2 (12%) ≥40 (20) Total (140) 2 (12%) 17 (100%) million people with a BMI > 27 Any obesity-related comorbidity 36 (29%) 46 (37%) 23 (19%) 18 (15%) 123 (100%) Hereof metabolic syndrome³ 21 (29%) 26 (36%) 14 (19%) 12 (16%) 72 (100%) 1Individuals without any of the following obesity related conditions: T2DM, Pre-diabetes, NASH, NAFLD, obstructive sleep apnea, osteoarthritis, PCOS, ASCVD, Heart failure, asthma, urinary incontinence, hypertension, chronic kidney disease stg. 3 or 4, musculoskeletal pain, dyslipideamia, metabolic syndrome; 3 Metabolic syndrome defined as two or more of dyslipidaemia; hypertension; prediabetes OR type II diabetes Source: Novo Nordisk real world research; National Health And Examination Survey (NHANES) cycles 2015-2016 and 2017-2018
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