Business Update & Financial Outlook

Remain committed to balanced capital allocation strategy $ Billions¹ Capital allocation order of priority $10.9 $2.6 $1.9 $1.0 $0.3 After-Tax R&D CapEx Dividends Paid Business Development 2 (ex-divestitures) Share Repurchase 1. Reflects Q2 spend. 2. Includes payment for the Prometheus acquisition. Continue to invest in our pipeline and business while augmenting our pipeline with value enhancing business development MERCK 19

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