Investor Presentation

108 Investor presentation First six months of 2022 Diabetes market share and market growth in International Operations Diabetes market growth and Novo Nordisk market share Diabetes market size and growth 160% 140% 120% 100% 80% 60% 40% 20% 0% May 2019 DKK billion ~13% 25% 5 9 22% 177 20% 15% 13% 200 10% 40% 5% ~22% 26% 26% 24% 0% May May Novo Nordisk AZ Others 2022 2021 May 2022 Novo Nordisk Competitors NN market share Market growth (right axis) NN share of growth NN growth (right axis) Source: IQVIA,May 2022, Value, MAT, all countries; NN: Novo Nordisk; AZ: Astra Zeneca Novo NordiskⓇ

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