Investor Presentaiton

140 Investor presentation Full year 2022 Obesity market share and market growth in North America Operations Obesity market growth and Novo Nordisk market share 100% 80% 60% 40% 20% Obesity market size and growth 94% 220% DKK billion 180% 115% 140% 100% 103% 9.3 60% 89% 20% 9.5 ~103% 18.9 0.1 94% ~115% NAO 0% -20% Nov 2019 NN market share Nov Nov Nov NN Obesity care Others 2021 2022 Market growth (right axis) NN growth (right axis) 2022 Source: IQVIA, Nov 2022, value, MAT, all countries; Share of growth not depicted due to too high numbers; NN: Novo Nordisk

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