Investor Presentation Full Year 2021

109 Investor presentation Full year 2021 GLP-1 market share and market growth in Rest of World 110% 70% 30% GLP-1 market growth and Novo Nordisk market share -10% Nov 2018 NN market share GLP-1 market size and growth Rest of World 80% 98% 13% DKK million ~32% 1.387 101 5.2 -72 60% 4.2 57% 40% 32% ~73% 20% 57% 44% 0% Nov 2021 Nov 2020 Novo Nordisk Eli Lilly Others Nov 2021 NN share of growth Novo Nordisk Competitors -Market growth (right axis)—NN growth (right axis) Source: IQVIA, Nov 2021, Value, MAT; NN: Novo Nordisk

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