Unlocking Hope for Cancer Patients Using PDT

ORAL PERIODONTAL DISEASES 19% OF GLOBAL ADULTS SUFFER FROM SEVERE PERIODONTAL DISEASES¹ Oral periodontal diseases are one of the major public health challenge in South-East Asia - WHO5 Increase in Prevalence over decades² 25 540,000,000 1,087,000,000 NUMBER OF CASES 1990 2019 RISK FACTORS³ Dietary factors: High Sugar, low-fibre diet Association: Diabetes, osteoporosis, plaque, smoking, tobacco • Genetics Age: Mostly older population Healthy Gums Plaque & Tartar Buildup Healthy Bone Level Pocket Unhealthy Gums Reduced Bone Level "20% of Implant patients suffer from peri- implantitis, which if left. untreated leads to implant loss."6 • CHALLENGES IN CURRENT TREATMENTS4 Need for accessibility to deep pockets without surgery Post-operative complications after surgery • Recurrence • Resistance development to antibiotics Side effects of antibiotic therapy, local inflammation Patient compliance https://www.who.int/news-room/fact-sheets/detail/oral-healthhttps://www.who.int/news-room/fact-sheets/detail/oral-health 2 https://onlinelibrary.wiley.com/doi/epdf/10.1111/odi.14436 3 https://www.perio.org/for-patients/gum-disease-information/gum-disease-risk-factors/v4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216136/ 4 Carranza's Clinical Periodontology- Tenth Edition 5 https://www.who.int/publications/i/item/9789290210061 6 https://pubmed.ncbi.nlm.nih.gov/28478213/ INVION

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