Q3 FY23 Earnings Presentation

Table of Executive Portfolio Financial Guidance & Contents Summary Highlights Highlights Assumptions ESG Appendix Growth Abbreviations & acronyms Business specific Business specific Other Other DD Double Digit AAA Abdominal Aortic Aneurysm MDI Multiple Daily Injection ACC HSD High-Single Digit AF Atrial Fibrillation MDT Medtronic ΑΙ American College of Cardiology IRS Artificial Intelligence Internal Revenue Service LBCT Late Breaking Clinical Trial LDD Low-Double Digit AID Automated Insulin Delivery NV Neurovascular ATTD Advanced Technologies and Treatments for Diabetes LGBTQ Lesbian, Gay, Bisexual, Transgender, Questioning LSD Low-Single Digit BP Blood Pressure PCI Percutaneous Coronary Intervention APAC Asia Pacific M Millions MSD Mid-Single Digit CGM Continuous Glucose Monitoring PFA Pulse Field Ablation. ANZ Australia, New Zealand N/A Not Applicable Revenue Decreased Y/Y CPV Coronary & Peripheral Vascular PH Pelvic Health B Billion NASS North American Spine Society Organic Revenue flat Y/Y New England Journal of CRHF Cardiac Rhythm & Heart Failure PTA Percutaneous Transluminal Angioplasty Bps Basis Points NEJM Organic Medicine Revenue Increased Y/Y Organic CRM Cardiac Rhythm Management RAS Robot-Assisted Surgery CAPEX Weighted Average WAMGR CRT-D Cardiac Resynchronization Therapy - RGR Respiratory, Gastrointestinal, & Renal CC Capital Expenditures Constant Currency Org Organic OUS Outside the United States Market Growth Rate Defibrillator CSF Cerebrospinal Fluid SAVR Surgical Aortic Valve Replacement CE Conformité Europëenne PLC Public Limited Company CST Cranial & Spinal Technologies SCS Spinal Cord Stimulation DJSI Dow Jones Sustainability Index Q Quarter DBS Deep Brain Stimulation SHA Structural Heart & Aortic EMEA Europe, Middle East, and Africa QQ Quarter-over-Quarter DCB Drug Coated Balloon SI Surgical Innovations EPS Earnings Per Share R&D Research & Development Environment, Social & DES Drug Eluting Stent SVD Structural Valve Deterioration ESG Rep Reported Governance DTM Differential Target Multiplexed Waveform TAA Thoracic Aortic Aneurysm EU European Union SEC U.S. Securities & Exchange Commission ENT Ear, Nose, & Throat TAVR Transcatheter Aortic Valve Replacement Ex-Vent Excluding Ventilator SG&A Selling, General & Administrative ECLS Extracorporeal Life Support TAVI Transcatheter Aortic Valve Implantation FDA Food and Drug Administration Tech Technology GI Gastrointestinal TDD Targeted Drug Delivery FX Foreign Exchange U.S. United States ICD Implantable Cardioverter Defibrillator TIR Time In Range FY Fiscal Year VBP Volume-Based Procurement ICM Insertable Cardiac Monitor TPS Transcatheter Pacing System GAAP Generally Accepted Accounting WE Western Europe Principles LRP Long Range Plan TTR Time in Target Range Investigational Device IDE WW Worldwide Exemption LVAD Left Ventricular Assist Device URO Urology ID&E Inclusion, Diversity and Equity YTD Year-to-Date Ex-MCS Excluding Mechanical Circulatory Support IPR&D In-process research and development Y/Y Year-over-Year 28 Q3 FY23 Earnings Presentation | February 21, 2023 Medtronic

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