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Investor Presentaiton

Investor Presentation First six months of 2018 Slide 84 SaxendaⓇ has rapidly grown value market share, but market development efforts are required to expand the market Despite strong SaxendaⓇ growth, US obesity care market remains small at around USD 787 million Generic AOM Novo Nordisk is investing in overcoming the barriers preventing effective obesity care Mindset SaxendaⓇ Other branded AOM TRX SU market share mUSD/value market share 100 800 7% 90 700 80 600 41% 70 500 60 83% 50 400 Few prescribers engaged 40 300 30 200 53% 20 100 Limited patient 10 14% 0 3% Volume Value Current state Acute weight loss focus with SaxendaⓇ stay- time ~5 months Key initiatives Advocate for chronic treatment through partnerships access Less than 3,000 physicians write ≥10 AOM prescriptions per month Only 2 in 5 of ~95 million adults with obesity have access to reimbursed medication Launch obesity educator programme Obtain Medicare coverage through support of "Treat and Reduce Obesity Act" AOM: Anti-obesity medication; TRX SU Volume Source: IQVIA NPA moving annual total through June 2018; NSP moving annual total through May 2018 changing diabetes® novo nordisk
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