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Investor Presentaiton

GSK Sales (£m) Performance: 12% HIV growth in 2022 driven by innovation portfolio 1,000 Momentum building across portfolio Growth driven by Dovato and long-acting regimens . 48% 800 44% 41% 38% 34% 600 29% 27% 25% 400 200 Q1 2021 Q2 2021 Q3 2021 Q4 2021 Q1 2022 Q2 2022 Q3 2022 Q4 2022 Apretude Juluca Dovato Rukobia Cabenuva Innovation as a % of total HIV sales . . Sales of £5.7bn in 2022 driven by two drug regimens and long-acting injectable portfolio Innovation sales of £2.5bn in 2022 - 43% of HIV portfolio Dovato sales of £1.4bn on track to become our #1 HIV product Cabenuva sales of £340m reflecting strong patient demand - now launched in all major markets Apretude sales of £41m - growing strongly in US SOLAR study and further pipeline data to be presented at CROI in February 19
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