ANNUAL REPORT 2021 slide image

ANNUAL REPORT 2021

LUNDBECK ANNUAL REPORT 2021 = CONTENTS 13/111 Maximize existing brands Enhance organizational agility and collaboration invest to grow Lundbeck Maintain focus on profitability Expand and Rebuild pipeline Expand operating space Figure 1: Lundbeck's strategic imperatives In the future, we will work with even more agility and collaboration across geographies, simplifying our processes and accelerating our ability to test and learn for faster, higher-quality decision making. This will fully leverage our diverse talent, knowledge and skillsets so that we can pursue solving some of the biggest brain disease challenges with the greatest patient reward. EXPAND AND INVEST TO GROW: OUR STRATEGIC IMPERATIVES Our strategic imperatives guide us towards reaching our objective to expand and invest to grow. Maximize existing brands Our strategic brands continue to show solid growth, both in volume and value, across all regions. At the same time, several of our mature brands have shown remarkable resiliency. Our commercial teams continue to accelerate our efforts in growing our mature and strategic brands across more geographies, thereby maximizing our existing brands to drive growth in the coming years. Our strategic brands BrintellixⓇ/TrintellixⓇ is a prescription medication used to treat major depressive disorder (MDD). The brand delivered solid growth in 2021 despite the flattening in total prescriptions of MDD medications in the U.S. during the pandemic. RexultiⓇ/RxultiⓇ is a prescription medication used as an adjunctive therapy to antidepressants for the treatment of MDD. We will continue to maximize this medication with launches in hopefully six additional markets in 2022. Abilify MaintenaⓇ is one of the most prescribed long acting injectable treatments for patients with schizophrenia. In some European countries it is the market leader. VyeptiⓇ is an infusion treatment for the prevention of migraine in adults. This is our newest strategic brand, launched in the U.S. in April 2020. We will continue to expand our geographical reach with approval in additional countries - in 2021 it was approved for use in Australia, Canada, the U.A.E., Kuwait, Switzerland and Singapore. Our mature brands Our portfolio of mature brands is large. In the U.S., NortheraⓇ, OnfiⓇ, SabrilⓇ and Xenazine® are declining after the initial loss to generics. The larger group of mature brands is remarkably resilient having high levels of trust and brand recognition in many markets around the world. And some of the products show continued growth, for example CipralexⓇ/LexaproⓇ. We continue our strong partnerships with Otsuka and Takeda Pharmaceutical Company Limited (Takeda) to engage healthcare professionals treating a broad range of psychiatric diseases, with keen commercial execution against our portfolio of strategic and mature brands. In the coming years, we will further strengthen and reinforce our field force ensuring that they have the digital tools and capabilities needed to help them to expand their networks and collaborate even better with patients and customers. We continue to ensure patients receive the full benefit of our medicines through continued clinical activities, life cycle management programs, proactive patient safety efforts, medical activities and value positioning, and also through advocacy efforts. Expand operating space We expanded our operating space through the acquisitions of Alder and Abide in 2019, which have given us the platforms needed to expand our areas of focus in neuroscience towards targeted indication groups of niche and rare neurology and psychiatry. Furthermore, we continue to invest in maximizing our strategic brand franchises BrintellixⓇ/Trintellix®, RexultiⓇ/RxultiⓇ, Abilify MaintenaⓇ and VyeptiⓇ, and we are continuously expanding our existing portfolio of medicines into new markets and additional indications.
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