DIMERIX INVESTOR CALL & PRESENTATION slide image

DIMERIX INVESTOR CALL & PRESENTATION

Two Phase 3 studies in COVID-19 patients Patients were randomised patients to receive one of: 1. 2. Angiotensin receptor blocker (ARB) alone Angiotensin converting enzyme (ACE) inhibitor alone ARB simultaneously with DMX-200 No RAS inhibitor (no placebo) 3. REMAP CAP 4. J NHMRC Clinical Trials Centre BB THE UNIVERSITY OF SYDNEY . REMAP-CAP: COVID-19 pneumonia in ICU >779 patients recruited to the study domain WHO endorsed study Primary endpoint = 21 day mortality Funded by European Union through H2020 "Rapid European COVID-19 Emergency Research response" (RECOVER) project CLARITY 2.0: COVID-19 respiratory complications Recruiting >600 patients in India and Australia Primary endpoint = 14 day WHO Clinical Health Score Run through the NHMRC Clinical trials centre and the University of Sydney Dimerix Secondary endpoint: recovery and quality of life post hospitalisation (long-COVID assessment) Initial study data anticipated Q1 2022 8
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