BenevolentAl Therapeutics Pipeline and Triage

Al used to extract meaningful information from biomedical literature at scale Automated Data Ingestion Source documents (e.g. Scientific Literature, Patents), extracted and normalised for into format optimised for BenevolentAl Natural Language Processing pipeline. Named Entity Recognition Entities mentioned in unstructured text are identified, normalised and grounded to BenevolentAl entities. Relationship Extraction NLP models extract meaningful relationships between identified entities using contextual information. NAME RELATIONSHIP Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) and Lou Gehrig's... SOD1 Is associated with, Syntactically-linked pairs (35k relations in 4.6k papers) ALS example extract above taken from a readout from the Benevolent Platform™ SOD1 mutation causes ALS phenotype in human MNs SOD1 mutation causes ALS phenotype in human MNs SOD1 ALS INFERRED FROM (CHEMBL) DISEASE CLASSIFICATION Motor Neuron Disease SOD1 Primary lateral sclerosis (PLS) is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs to a group of disorders known as motor neuron dise... ALS Al Benevolent 13

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