Investor Presentaiton

GUARDANT™ Smart Liquid Biopsy platform о The power of liquid biopsy Simple blood draw Enhanced by epigenomics • Deeper tumor sensing . • Tissue-site agnostic • Wider biological view Captures whole body heterogeneity • Captures temporal dynamics INVESTOR 20 DAY 23 . Delivering performance & scale Proprietary biochemistry with high sensitivity / specificity Efficient COGS Powered by data generation at scale Delivers 100X genomic breadth and >50X sensitivity with no additional cost 24

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