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Investor Presentaiton

Segment (Healthcare) Chromatography: Demand is expanded for diabetes treatments applications in Europe, the United States, and Asian markets APIs and their intermediates : Sales of nucleic acid drug substances, anti-ulcer drug intermediates, and insomnia treatment drug intermediates expanded Expansion plans: Completion of new silica gel production facility by 2024 at Matsuyama Plant, Promoting expansion plans for completion of new silica gel production facility and expansion by 2026 at Amagasaki Plant Net sales -Operating income (Millions of yen) Variance (Operating income, YoY) 5,273 5,372 2,661 2,307 1H FY2022 X 1H FY2023 Net sales (up ¥0.1 billion YoY) Chromatography* APIs and Their Intermediates +0.1 +0 2.3 1H FY2022 * * Pharmaceutical purification materials(Silica gel), analytical equipment, packed columns *Figures by segment for FY2022 are approximate figures reclassified into new segments Something Better with Chemicals Sales unit Feedstock price costs +0.2 (0.1) Production and sales volume +0.5 (Billions of yen) Fixed costs (0.3) 2.6 1H FY2023 OSAKA SODA 7
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