Reshaping the HIV treatment and prevention landscape slide image

Reshaping the HIV treatment and prevention landscape

Key growth drivers: opportunities and investment priorities Illustrative Vaccines Specialty Medicines General Medicines More than 5% CAGR + Shingrix + Meningitis + Dovato + Cabenuva + Zejula + Blenrep + Jemperli* + Benlysta + Nucala + RSV + Men ABCWY + Cab PrEP + Zejula + Blenrep + Jemperli + depemokimab ('294) + otilimab + daprodustat 2021 + Trelegy + gepotidacin Marketed assets Late-stage Pipeline 2026 Vaccines high single digit CAGR 2021-26 Shingrix - double revenues in 5 years gsk Meningitis - aim to double revenues in 10 years dolutegravir RSV - £Multi-billion peak year sales conotidacin ↑ LAMIV CONTIDOS Flu - new strategy to double revenues in 10 years LOD + base decine Growu anivers 2031 Cany pipelineT DD Note: Bars are not at scale. All outlook and ambition statements are given on a constant currency basis and use 2021 forecast exchange rates as a base, assuming a continuation of Q1 2021 closing rates. See basis of preparation and assumptions in Appendix. CAGR is for the 5 years to 2026, using 2021 as the base year. Pipeline sales are risk-adjusted and include anticipated sales of new products and Life Cycle Innovation (LCI) launched from 2021 onwards. Note: COVID therapeutic and vaccine solutions are excluded from the above. Assets highlighted reflect major contributions to growth in period shown. *Tesaro asset 63
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