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Investor Presentaiton

SELECT TRIALS - EARLY PHASE DIABETES AND OBESITY (CONT.) Lilly Molecule Study Indication* Title Phase Patients DACRA QW II NCT05380323 Obesity A Study of LY3541105 in Healthy and Overweight Participants 1 160 GIPR Agonist LA II NCT05407961 Diabetes Mellitus, Type 2 A Study of LY3532226 in Participants With Type 2 Diabetes Mellitus 1 92 Primary Outcome** Number of Participants with One or More Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration Part A: Number of Participants with One or More Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Event(s) (SAEs) Considered by the Investigator to Primary Completion Completion Oct 2023 Oct 2023 Oct 2023 Oct 2023 Nisotirostide Diabetes (PYY Analog NCT05377333 Agonist) Mellitus, Type 2 A Study of LY3457263 Alone and in Combination With Dulaglutide (LY2189265) in Participants With Type 2 Diabetes 1 86 be Related to Study Drug Administration Number of Participants with One or More Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Nov 2023 Nov 2023 Amylin Agonist LA NCT05295940 Obesity A Study of LY3841136 in Healthy and Overweight Participants 1 160 Related to Study Drug Administration Number of Participants with One or More Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Jan 2024 Jan 2024 * Molecule may have multiple indications ** Trial may have additional primary and other secondary outcomes Not for promotional use Related to Study Drug Administration Source: clinicaltrials.gov, July 14, 2023 2023 Q2 EARNINGS 52 62
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