Investor Presentation Full Year 2021

98 Investor presentation Full year 2021 Diabetes market share and market growth in EMEA 80% 60% 40% 20% 0% Diabetes market growth and Novo Nordisk market share -20% Nov 2018 Diabetes market size and growth EMEA DKK -8% 20% billion 2 99 3 2 92 15% 42% 29% 10% 12% 8% 5% ~12% 29% 28% 0% Nov 2021 Nov Novo Nordisk AZ Others Nov 2020 2021 Novo Nordisk Competitors -NN market share -Market growth (right axis) NN share of growth NN growth (right axis) Source: IQVIA, Nov 2021, Value, MAT, EMEA: Europe, Middle East and Africa; NN: Novo Nordisk; AZ- Astra Zeneca

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