Orthofix Investor Presentation Deck

● ● ● Orthofix Growth Drivers: Near Term. Meaningful opportunities to grow within current significant markets M6-C DISC Attracting new users Comprehensive training program Collecting clinical data $800 million market opportunity ● ● FITBONE Strong early adoption Only internal limb lengthener with adult & pediatric FDA approval Recently performed first U.S. pediatric case $600 million market opportunity ● ● ● INTERBODIES Comprehensive interbody offering (PEEK, PTC, 3D- Printed Ti, and Expandable) Accelerating adoption Innovative new product introductions $1.6 billion market opportunity ● ● ● ● ● BIOLOGICS Building a robust portfolio Leveraging MTF Biologics partnership and portfolio: TrinityTM, VirtuosTM, Fiberfuse™ and Legacy™ Introduced differentiated synthetic solutions Driving incremental pull-through $2.1 billion market opportunity ● ● ACCELSTIM Ultrasound technology Expands BGT nonunion fracture portfolio Provides new fresh fracture indication Doubles Orthofix long bone market opportunity $250 million market opportunity ORTHOFXxX ORTHOFIX 14

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