Cytek Investor Day Presentation Deck

Mapping the landscape of the lung in pneumococcal pneumonia nature D Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity Shenoy et al, 2022 COMMUNICATIONS Epithelial cells H+H Day: 0 1 ↓↓↓↓ T and B lymphocytes ● 7 Watch recovery from pneumonia & development of immunity ● + 8 10 14 24 ↓↓ ↓ ↓ 35 Spectral fingerprints of lung cells are generated on Cytek Aurora Measurement stability over multiple timepoints - critical for this project Recovery from pneumonia induces development of tissue resident memory CD4+ TRM cells, BRM cells, and antibody secreting plasma cells.

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