AMD Results Presentation Deck

15 FY 2021 SUMMARY P&L-NON-GAAP¹ ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expenses/Revenue % Operating Income Operating Margin % Net Income Earnings Per Share¹ Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 2021 $16,434 $7,934 48% $3,877 24% $4,069 25% $3,435 $2.79 1. 2020 $9,763 $4,353 45% $2,696 28% $1,657 17% $1,575 $1.29 Y/Y Up 68% Up 82% Up 370bps Up 44% Down 4pp Up 146% Up 8pp Up 118% Up 117% Includes a higher tax rate beginning in Q1 2021. See Appendices for GAAP to Non-GAAP reconciliation and share count reference AMD

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