Certara Investor Presentation Deck

Reconciliation of Net Income (Loss) to Adjusted EBITDA Net income (a) Interest expense(a) Interest income (a) Provision for income taxes(a) Depreciation and amortization expense(a) Intangible asset amortization(a) Currency (gain) loss (a) Equity-based compensation expense(b) Acquisition-related expenses(d) Transaction-related expenses(e) Loss on disposal of fixed assets(f) First-year Sarbanes-Oxley implementation costs(g) Adjusted EBITDA © Copyright 2022 Certara, Inc. All rights reserved. THREE MONTHS ENDED MARCH 31 2021 $ $ 2022 (in thousands) $ 2.210 3,228 (11) 1,536 482 12,450 (705) 7,513 272 17 5 653 27,650 27 1,052 3,928 (70) 527 602 10,102 191 5,151 1,596 685 107 23,871 CERTARA

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