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Investor Presentaiton

Performance: ongoing evolution to Specialty Medicines and Vaccines Commercial excellence sharpened, with focus on newer, growing products Sales (£bn) Specialty Medicines and Vaccines Progress of priority growth drivers 20 2% 20 % 70% 12 42% 62% 18 58% 58% 55% 60% 10 16 50% 46% 14 50% 12 40% 30% Sales (£bn) 8 33% 28% 22% 6 0 20% 4 13% 4 7% 2 10% 2 0 0% 0 2017 2018 2019 2020 2021 2022 2017 2018 2019 2020 2021 2022 HIV Other Specialty Medicines Vaccines % GSK sales Shingrix Nucala Meningitis Benlysta Trelegy Oncology HIV 2DRs cabotegravir % GSK sales Absolute values at AER; 2017-20 figures assume GSK sales to be former GSK Group (pre-demerger) less Consumer Healthcare. 2021-22 figures prepared on a continuing operations basis; all figures exclude COVID-19 solutions. GSK 18
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