Investor Presentaiton

Shield addresses existing challenges to CRC screening Challenges in CRC screening 1-3 Addressed by Shield Long Colonoscopy wait times. Unpleasant experience Time consuming, multi-step patient participation INVESTOR 20 DAY 23 Simple blood draw GUARDANT™ 1. US Preventive Services Task Force. JAMA. 2021;325(19):1965-1977 2. Muthukrishanan M, et al. Prev Med Rep. 2019;15:00896. 3. Melson JE, et al. Clin Gastroenterol Hepatol. 2020 Nov;18(12):2667-2678.e2. 3. US Preventive Services Task Force. JAMA. 2021;325(19):1965 115

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