1Q22 Business Results

Promoting Sales Growth through Distribution Channels Improvement & Portfolio Expansion Improved Distribution Channel (Increased direct-sales %) * Direct-sales% relative to the market size 1% 30% 90% 2016 2022 2025(E) Product Diversification (Portfolio Expansion) 2 >>>> 7 11 *num. of Biologics Investor Relations 2022 13

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