Investor Presentaiton

INOVIO INO-4800 Rapid Response Species . • • Mouse • Guinea Pig (ID delivery) Rabbit (full human dose) . NHP (immunogenicity/challenge) . Ferret (challenge) CSIRO First Subject Treated in Phase 1 Trial April 6th, 2020 о 2/02 2/09 2/16 2/23 3/01 3/08 3/15 3/22 3/29 4/06 4/10 5/20 6/30 7/30 nature COMMUNICATIONS Feb 4th Submitted In vitro expression data XXXX THE WISTAR INSTITUTE ● T cell data Ab data Immunization ACE2/Spike blocking Biodistribution nature COMMUNICATIONS Pseudovirus neut. Public Health England Published Live virus neut. INOVIO POWERING DNA MEDICINES

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