Evotec Results Presentation Deck
evotec
"Evotec Inside" Fully invested pipeline gaining visibility
Progress of drug candidates in advanced stages
Selected pipeline events within next 18 - 24 months
• Phase III data (China) with JingXin in insomnia
• Phase Ilb data with Bayer in RCC (eliapixant)
• Phase II data with Bayer in Overactive bladder (eliapixant)
• Phase II with Bayer in Endometriosis (eliapixant)
• Phase II with Bayer in Neuropathic pain (eliapixant)
Phase II with Bayer in Gynaecology (B1 antagonist)
• Phase I data in Chikungunya virus
Phase I initiation with BMS in CNS
• Phase I data with Exscientia in Oncology (A2a)
• Phase I initiation with Kazia in Oncology (EVT801)
Phase I with Sanofi in HBV
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Multiple co-owned equity companies will progress
in clinic (e.g. Topas, Forge, Carrick, Fibrocor, ...)
Clinical
Pre-clinical
Discovery
Molecule
EVT201
BAY-1817080
Therapeutic Area/Indication
Insomnia (GABA-A)
Chronic cough (P2X3)
BAY-1817080 Overactive bladder
BAY-1817080 Neuropathic pain
BAY-1817080
Endometriosis
CT7001
CT7001
EVT401
BAYXXX
BAY2328065
BI 894416
BI 860585
TPM203
DSP-1181
CNTX 6016
EVT894
BAYXXX
EVT801
APN411
EXS21546
GLPGXXXX
BAYXXXX
QRB001
BMSXXXX
EVT895
EVTXXXX
Oncology (CDK7)
Oncology (CDK7)
Immunology & Inflammation (P2X7)
Women's health
Gynaecology
Asthma (not disclosed)
Oncology (mTORC1/2)
Pemphigus Vulgaris (not disclosed)
Obessive-compulsive disorder (5-HT1A)
Pain (CB2)
Chikungunya (Antibody)
Endometriosis (not disclosed)
Oncology (VEGFR3)
Oncology - Immunotherapy
Oncology (various programmes)
Fibrosis (not disclosed)
Nephrology (not disclosed)
Metabolic Diabetes (not disclosed)
Neurodegeneration (not disclosed)
HBV
CNS, Metabolic, Pain ...
Partner
入京新药业
INGAN PHARMACEUTICAL
Carrick
12 occutics
Carrick
12occutics
克斯坦奥集团
CONEA GROUP
BAYER
Boehringer
Ingelheim
Boehringer
Ingelheim
Topas Therapeutics
Exscientia
Boehringer
Ingelheim
NIH SANOFI
SANOFI
SIOLOGICS
SANOFI APEIRON
Exscientia
Galápagos
QRbeta
THE RAFELTICS
Bristol Myers Squibb
SANOFI
>10 further programmes
Discovery Pre-clinical Phase I
Phase II
Multiple programs across nephrology, oncology, immunology among other therapeutic areas
Phase IIIView entire presentation