Investor Presentation Full Year 2021

93 Investor presentation Full year 2021 Diabetes market share and market growth in International Operations Diabetes market growth and Novo Nordisk market share Diabetes market size and growth DKK billion 170% 20% -6% 3 2 186 6 175 140% 16% 14% 110% 12% 80% 50% 20% -10% Nov -NN market share 2018 -NN share of growth -Market growth (Right axis) Source: IQVIA, Nov 2021, Value, MAT, all countries; NN: Novo Nordisk; AZ: Astra Zeneca 54% 8% 25% 6% 4% 23% ~14% 25% Nov 0% Nov Novo Nordisk AZ Others Nov 2021 2020 2021 Novo Nordisk Competitors Novo NordiskⓇ

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