Investor Presentaiton

Business and profit growth leveraging our geographic diversification Digital customers Customer Customer loans deposits Net operating income Underlying att. profit Underlying ROTE Q1'21 (vs. Q1'20) (mn) (EUR bn) (EUR bn) (EUR mn) (EUR mn) 15.6 558 576 2,077 Europe +9% +2% +7% +36% 826 +338% 8% +6.6 pp North 6.3 123 105 1,620 773 14%2 America +13% -1%1 +9%1 +4% +205% +9.0 pp South 21.6 120 103 2,320 America +21% +10% +17% +12% 773 +41% 19% +3.4 pp Digital Consumer Bank 0.7 116 53 703 291 12% +26% -1% +7% +1% +25% +2.4 pp Santander Note: YoY changes in constant euros. Loans and advances to customers excluding reverse repos. Customer deposits excluding repos (1) Excluding Puerto Rico and Bluestem disposal impact. Otherwise, loans -4% and deposits +5% (2) ROTE adjusted for excess capital in the US: 22% 51

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