Q1 2022 Results
Company overview
Financial review
Financial performance
CRM
Immunology
Neuroscience
2022 priorities
Innovation: Pipeline overview
Ophthalmology
Appendix
References
Innovation: Clinical trials
Abbreviations
Respiratory & Allergy
Oncology: Solid Tumors
Hematology
Biosimilars
Global Health
Tafinlar + MekinistⓇ - BRAF inhibitor and MEK inhibitor
Study
Indication
Phase
Patients
Primary Outcome
Measures
Arms Intervention
NCT04940052 (CDRB436J12301)
Thyroid cancer
Phase 3
150
Progression Free Survival
Arm 1: Experimental: Dabrafenib plus trametinib
Participants will be treated with dabrafenib twice daily and trametinib once daily
Arm 2: Placebo Comparator: Placebo dabrafenib plus placebo trametinib
Participants will receive placebo dabrafenib twice daily and placebo trametinib once
daily
Previously treated patients with locally advanced or metastatic, radio-active lodine
refractory BRAFV600E mutation-positive differentiated thyroid cancer
Target Patients
Read-out Milestone(s)
2024
Publication
TBD
99 Investor Relations | Q1 2022 Results
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