Capital Markets Day: Commercial Execution and Innovation in Obesity Care slide image

Capital Markets Day: Commercial Execution and Innovation in Obesity Care

12 Commercial execution and innovation Obesity care There remains a large opportunity for activating more people with obesity to seek treatment WegovyⓇ patient characteristics in the US Despite the early success of WegovyⓇ, activating patients remains the focus ONCE-WEEKLY wegovy semaglutide injection 2.4 mg 75% . 81% Female Average BMI 38.8 of patients new to anti- obesity medication1 • 38% have ≥3 co-morbidities Of the people with overweight or obesity in the US, almost 90% have a weight-related comorbidity YOU'RE READY for THE TRUTH BMI 27-30 30-35 35-40 ≥40 140 Total (million of people) (43) (52) (25) (20) it's million people with a BMI > 27 No obesity-related comorbidity² Any obesity-related comorbidity 7 6 2 2 17 BIGGER 36 46 23 18 123 than ME Hereof metabolic syndrome³ 21 26 14 12 72 1 Patients new to anti-obesity medication reflect source of business, where 75% of patients starting WegovyⓇ are naïve to anti-obesity medication treatment and 25% have either switched from or restarted anti-obesity treatment, IQVIA Feb. 2022; 2 Individuals without any of the following obesity related conditions: T2DM, Pre-diabetes, NASH, NAFLD, obstructive sleep apnea, osteoarthritis, PCOS, ASCVD, Heart failure, asthma, urinary incontinence, hypertension, chronic kidney disease stg. 3 or 4, musculoskeletal pain, dyslipideamia, metabolic syndrome; 3 Metabolic syndrome defined as two or more of dyslipidaemia; hypertension; prediabetes OR type II diabetes Source: Novo Nordisk real world research; National Health And Examination Survey (NHANES) cycles 2015-2016 and 2017-2018 Novo NordiskⓇ CMD22 CAPITAL MARKETS DAY
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