Q4 2022 Results slide image

Q4 2022 Results

Company overview Financial review 2023 priorities Appendix INNOVATION Prioritizing pipeline to high-value innovative medicines Refining our proven development engine with greater focus on asset value and improving R&D productivity Proven development engine Improving R&D productivity Total NME approvals by company (1999-2021)1 42 34 == 1 Clear TA strategy with disease area prioritization 30 NDA 12 BLA 28 20 23 23 18 14 Novartis Company A Company B Company C Company D Company E 2 Early assets with integrated development plans, until submission 3 Ongoing tracking and evaluation of asset progression/value 4 End-to-end governance with clear processes and ownership Expected outcomes Improved overall success rate (discovery to approval) ☐ Cycle time reduction Increased asset value ✓ Industry leader across first-in-class approved NMEs² 1. US FDA NME approvals. 2. FDA: BCG analysis (2017-2021). 10 Investor Relations | Q4 2022 Results NOVARTIS | Reimagining Medicine
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