Ocuphire Pharma Investor Day Presentation Deck

Diabetic Retinopathy is a Progressive, Vision Threatening Disease DME Losing Vision is Diabetic Patients Top Concern DR 25 Going Blind Amputation, losing a leg Cardiovascular/heart problems Other Eye Problems Foot problems Kidney problems What are the top concerns for diabetic patients? |||||| 0% 5% 10% 15% 25% 20% 25% Percent Responders Source: Patient survey adapted from Lions International Foundation and International Diabetes Foundation-Europe; Meltzer 2000 30% 30% 35% 35% 35% 38% 40% N=2702 40% 45% Ocuphire PHARMA

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