Q1 2023 Results slide image

Q1 2023 Results

Company overview Financial review Conclusions Appendix References ScemblixⓇ maintains strong launch momentum Sales evolution USD m Ex-US US 52 10 41 31 25 76 15 61 42 37 29 25 Q1 Q2 Q3 Q4 Q1 2022 2023 TKI tyrosine kinase inhibitor. GROWTH OSCEMBLIX® (asciminib) 20 mg. 40 mg tablets Q1 sales USD 76 million; US NBRx share at 32%¹ Sales driven by patients resistant/intolerant to other TKIs Global rollout ongoing with approval in 46 countries; access pathways in 19, negotiations ongoing in 30+ Increasing recognition of efficacy and tolerability benefit: G-BA granted the highest ever rating for a medicine in CML ASC4FIRST (1L registrational study) completed enrollment ahead of plan, readout and filing expected 2024 NBRX-new to brand prescription. G-BA- German national payer (Gemeinsamer Bundesausschuss). 1. IQVIA: US Jan 2023 rolling three months 3L+ new patient start share. 20 Investor Relations | Q1 2023 Results ✓ NOVARTIS | Reimagining Medicine
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