Investor Presentaiton

4 Commercial execution and innovation Diabetes care Diabetes prevalence increases, yet only ~50% of people with diabetes are diagnosed and even fewer reach HbA1c target In 2045, 784 million adults are expected to live with diabetes 1 in 2 adults go undiagnosed and more treated patients should reach their HbA1c target Million 1,000 1 in 10 have diabetes 800 643 600 537 400 200 1 in 8 have diabetes 537m 784 35m Novo NordiskⓇ 2021 2030 2045 Prevalence Diagnosed Treated Reach target Treated for complications EMEA Region China Rest of World North America Prevalence Novo Nordisk products Note: Region China is the Western Pacific number, i.e. also includes Australia which in NN's regions belongs to Rest of World Source: Diabetes prevalence and diagnosed are based on Diabetes Atlas 10th edition, 2021; Treated is based on IQVIA patient data; real-world studies indicate between 30-55% of patients reach HbA₁ target <7% .e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388968/ CMD22 CAPITAL MARKETS DAY

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