Half-Year 2022 Financial and Clinical Trials Update slide image

Half-Year 2022 Financial and Clinical Trials Update

Pharma Division CER sales growth¹ in % Top 20 products by region Roche US Europe Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Japan Q4 International Q1 Q2 Q3 Q4 Q1 Q2 Ocrevus 0 23 12 10 36 26 34 34 35 51 29 62 Perjeta 2 -2 -1 4 -8 -8 -21 -12 0 -3 -1 Hemlibra 36 33 28 24 26 53 31 29 Tecentriq 10 2 10 15 16 41 14 24 Actemra/RoActemra 143 67 22 -31 10 18 -4 -2 Herceptin -52 -34 -26 -29 -20 -3 -13 -9 2225 29 30 15 24 75 34 -5 -9 -37 -36 -30 -27 Avastin -50 -45 -39 -36 MabThera -49 -32 -20 -24 Kadcyla 0 3 Xolair 8 14 Alecensa 9 18 32001 -69 -49 -56 -49 5 LO -33 -13 -19 -16 -1 16 16 8 12 550 TE523222 -1 16 24 32 37 138 55 63 115 62 24 0 17 5 12 -2 -14 -55 -30 -44 -7 17 -18 -3 222 -30 0 -12 -13 -17 -15 59 42 28 -11 -24 -23 -17 13 25 14 7 9 5 80 11 LO FLO LO Ronapreve - -61 -99 -2 -25 -15 -23 -13 20 16 38 26 81 7 5 40 25 45 29 -68 ៩៤ 3778 25 280 Lucentis -10 2 -26 -9 1 TNKase/Activase 2 * 22 -21 1 17 7 -3 4 Evrysdi 112 36 28 227 * * -5 Esbriet -2 -7 -4 -28 0 0 -5 1 -73 -36 -36 -36 Gazyva 3 * 11 0 3 10 2 -5 -8 10 -7 8 -10 43 56 75 101 Phesgo 236 187 134 * * * 188 278 Pulmozyme -10 6 0 5 -10 -15 -11 -12 -18 CellCept -18 -31 -15 -17 -2 3 -7 -7 292 22 11 44 -7 -9 -8 -9 18 = 12 22 45 13 w& -4 14 3 -14 3 CER = Constant Exchange Rates; * over 500%; 1Q3-Q4/21 vs Q3-Q4/20; Q1-Q2/22 vs Q1-Q2/21 168
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